Atherosclerosis: Experimental Methods and Protocols (Methods in Molecular Medicine). Angela F. Drew

Atherosclerosis: Experimental Methods and Protocols (Methods in Molecular Medicine)



Download Atherosclerosis: Experimental Methods and Protocols (Methods in Molecular Medicine)



Atherosclerosis: Experimental Methods and Protocols (Methods in Molecular Medicine) Angela F. Drew ebook pdf
Publisher:
Language: English
Page: 247
ISBN: 0896037517, 9781592590735

Review

"Methods for setting up animal model periments and special assays of blood and cellular moments of the pathologic processes involved are thoroughly described and referenced. Newly emerging animal models based on genetic manipulation are described in depth, with sufficient detail to broaden the scope of research by seasoned investigators to permit the novice to enter this field. ...Anyone working in vascular pathology and atherosclerosis research will find a wealth of practical information describing modern research methods." - Clinical and Applied Thrombosis/Hemostasis "Atherosclerosis is recommended for academic health science libraries. It is also recommended to individual laboratories that conduct research in the area of atherosclerosis or heart disease." -E-STREAMS

From the Back Cover

Atherosclerosis-a major killer of people in Western societies-is not yet completely understood. In Atherosclerosis: Methods and Protocols, Angela Drew and a panel of experts have assembled a comprehensive collection of traditional and cutting-edge techniques for investigating this disease and its possible treatments. Each readily reproducible method includes step-by-step instructions and practical information regarding sample collection, the choice of animal model system, experimental design, and practical data analysis techniques. Assay systems for serum or plasma determination of lipoproteins are also described, along with assays for those plasma proteins recently identified as implicated in atherogenesis, including cholestryl ester transfer protein, homocysteine, glycated lipoproteins, and apolipoprotein(a). Additional techniques cover the isolation and culture of cells and glycosaminoglycans from atherosclerotic plaques, and the collection and analysis of experimental atherosclerotic lesions. Comprehensive and richly detailed, Atherosclerosis: Methods and Protocols enables all biomedical investigators to select those optimized techniques that may be most fruitfully used to study the development, progression, and treatment of atherosclerotic lesions today.



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